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Svetlana Altamentova
Svetlana is a research technician in the structural Proteomics group working now on the IclR project.
She is focusing on the investigation of the molecular mechanisms of ligand binding to the proteins of the IclR familly.
Before joining the lab, she was working in the Center for Cardiovascular Research in Toronto General Hospital and in the Sackler Institute of Molecular Medicine in the Tel-Aviv University. She has received her M.Sc. in Biochemistry from the Belorussian State University, Minsk, Belarus.
email: saltamen@uhnres.utoronto.ca
phone: 416-946-0074
Selected publications
- Fedak P.W.M., Altamentova S.M., Weisel R.D., Nili N., Verma S., Lee T-Y. J., Kiani C.,
Mickle D.A.G., Strauss B. H., Li R-K. "TIMP-3 regulates matrix remodeling in experimental
and human heart failure." Am. J. Physiol. Heart Circ. Physiol., 284: H626-H634, 2003.
- Merante F., Altamentova S. M., Mickle D. A. G., Weisel R. D., Thatcher B. J., Martin B. M., Marshall J. G., Tumiati L. C., Cowan D. B., Li R-K "The characterization and purification of a human transcription factor modulating the glutathione peroxidase gene in response to oxygen tension." Molecular and Cellular Biochemistry, 229: 73-83, 2002.
- Altamentova S. M. and Shaklai N. "Oxidative stress in b-thalassemia: hemoglobin a-chains activate peroxidation of low density lipoproteins." BioFactors, 8: 169-172, 1998.
- Altamentova S. M., Shaklai N., Arav R., Miller Y.I. "A fluorescent method for estimation of toxemia: binding capacity of lipoproteins and albumin in plasma." Clin. Chim. Acta, 271: 133-149, 1998.
- Miller Y. I. Altamentova S. M., Shaklai N. "Peroxidation of low-density lipoprotein by hemoglobin stems from a heme-initiated globin radical: antioxidant role of haptoglobin." Biochemistry, 36: 12189-12198, 1997.
- Altamentova S. M., Marva E., Shaklai N. "Oxidative interaction of unpaired hemoglobin chains with lipids and proteins: a key for modified serum lipoproteins in thalassemia." Arch. Biochem. Biophys., 345: 39- 46, 1997.
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