Watson CPN, Morshead CM, van der Kooy D, Evans RJ (1988) Postherpetic
Neuralgia: A postmortem analysis. Pain 34: 129-138.
Morshead CM, van der Kooy D (1990) Separate blood and brain origins
of proliferating cells during gliosis in adult brains.
Brain Research 535: 237-244.
Watson CP, Deck JH, Morshead C, van der Kooy D, Evans RJ. (1991)
Post-herpetic neuralgia: further post-mortem studies of cases with
and without pain. Pain 44:105-17.
Morshead CM, van der Kooy D (1992) Postmitotic death is the fate
of constitutively proliferating cells in the subependymal layer of
the adult mouse brain. J Neurosci 12(1): 249-256.
Wen JYM, Morshead CM and van der Kooy D (1994) Glial proliferation
after axotomy is induced by a mitogenic factor released from injured
neurons. J Cell Biol 124: 1005-1015.
Morshead CM, Reynolds BA, Craig CG, McBurney MW, Staines WA,
Morassutti D, Weiss S, van der Kooy D (1994) Neural stem cells in
the adult mammalian forebrain: A relatively quiescent subpopulation
of subependymal cells. Neuron 13(5): 1071-1082.
Craig CG, Tropepe V, Morshead CM, Reynolds BA, Weiss S, van der Kooy D
(1996) In vivo growth factor expansion of endogenous subependymal neural
precursor cell populations in the adult mouse brain.
J Neurosci 16(8): 2649-2658.
Weiss S, Reynolds BA, Vescovi AL, Morshead C, Craig CG, van der Kooy D
(1996) Is there a neural stem cell in the mammalian forebrain?
Trends Neurosci 19: 387-393.
Tropepe V, Craig CG, Morshead CM, van der Kooy D (1997) Transforming
growth factor alpha null and senescent mice show decreased neural progenitor
cell proliferation in the forebrain subependyma.
J Neurosci 17(20): 7850-7859.
Morshead CM, Craig CG, van der Kooy D (1998) In vivo clonal analysis of
endogenous neural stem cell proliferation in the adult mammalian forebrain.
Development 125: 2251-2261.
Chiasson BJ, Tropepe V, Morshead CM, van der Kooy D (1999)
Adult mammalian forebrain ependymal and subependymal cells demonstrate
proliferative potential, but only subependymal cells have neural stem cell
characteristics. J Neurosci 19:4462-4471.
Craig CG, D'Sa R, Morshead CM, Roach A, van der Kooy D (1999)
Migrational analysis of the constitutively proliferating subependymal
cells in the adult forebrain. Neurosci 93(3): 1197-1206.
Morshead CM, van der Kooy D (2000) A cell survival factor
(N-acetyl-L-cysteine) alters the in vivo fate of constitutively
proliferating subependymal cells in the adult forebrain.
J Neurobiol 42:338-346.
Morshead CM, van der Kooy D (2001) A new spin on neural stem cells?
Curr Opin Neurobiol 11: 59-66.
Morshead CM, Benveniste P, van der Kooy D, Iscove, NN (2002)
Hematopoietic competence is a rare property of neural stem cells and
may depend on cell transformation and genetic mutation.
Nature Medicine, 8(2): 268-273
(including News and Views commentary).
Morshead CM, Garcia AD, Sofroniew MV, van der Kooy D (2003)
The ablation of GFAP positive cells from the adult CNS results in the
loss of forebrain neural stem cells but not retinal stem cells.
Eur J Neurosci 18: 76-84.
Kim M, Morshead CM (2003) Distinct populations of forebrain neural
stem and progenitor cells can be isolated using side-population analysis.
J Neurosci 23: 10703-10709.
Morshead CM, van der Kooy D (2004) Disguising adult neural stem cells.
Curr Opin Neurobiol 14: 125-131.
Zhang R, Zhang Z, Wang L, Wang Y, Gousev A, Zhang L, Ho KL, Morshead C,
Chopp M (2004) Activated neural stem cells contribute to stroke induced
neurogenesis and neuroblast migration toward the infarct boundary in rats.
J Cerebral Bl Flow and Metab. 24:441-448.
Morshead CM (2004) Neural stem cells in vivo: Solving the identity
crisis. Developmental Neurosci 26: 93-100.
Karpowicz P, Morshead CM, Kam A, Jervis EJ, Ramunas J, Cheng V,
van der Kooy D (2005) Support for the immortal strand hypothesis: neural
stem cells partition DNA asymmetrically in vitro.
J Cell Biol 170: 721-732.
Goraltchouk A, Scanga V, Morshead CM, Shoichet MS (2006)
Incorporation of protein-eluting microspheres into biodegradable nerve
guidance channels for controlled release. J Con Release 110: 400-407.
Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Morshead CM,
Fehlings MG (2006) Delayed transplantation of adult neural stem
cells promotes remyelination and functional neurological recovery
after spinal cord injury. J Neurosci 26(13): 3377-89.
Erlandsson A, Morshead CM (2006) Exploiting the properties of adult
stem cells for the treatment of disease.
Curr Opin Molecular Therapeutics 8: 331-337.
Ramunas J, Illman M, Kam A, Farn K, Kelly L, Morshead CM,
Jervis EJ (2006) Identification of a behavioral phenotype in neural
stem cell cultures: Lineage informatics of undifferentiated
neurosphere-derived cells. Cytometry A 69:1202-1211.
Willaime-Morawek S, Seaberg RM, Batista C, Labbe E, Attisano L,
Gorski JA, Jones KR, Kam A, Morshead CM, van der Kooy D (2006) Embryonic
cortical neural stem cells migrate ventrally and persist as postnatal
striatal stem cells. J Cell Biology, 175:159-168.
Kolb B*, Morshead CM*, Gonzalez C, Kim M, Gregg C, Shingo T, Weiss S
(2007) Growth factor-stimulated generation of new cortical tissue and
functional recovery after Ischemic damage to the motor cortex of rats.
J Cereb Blood Flow and Metab, 27:983-987. *contributed equally to the work.
Eftekharpour E, Karimi-Abdolrezaee S, Cheng V, Wang J, El-Beheiry H,
Morshead CM, Fehlings MG (2007) Myelination of congenitally dysmyelinated
spinal cord axons by adult neural precursor cells results in formation of
nodes of Ranvier and improved axonal conduction.
J. Neurosci, 27(13):3416-28.
Zahir T, Nomura H, XiaoDong G, Kim H, Tator C, Morshead CM, Shoichet MS
(2008) Bioengineering neural stem/progenitor cell-coated tubes for spinal
cord injury repair. Cell Transplant, 17(3):245-54.
Nomura H, Zahir T, Kim H, Katayama Y, Kulbatski I, Morshead CM,
Shoichet MS, Tator C (2008) Extramedullary chitosan channels promote
survival of transplanted neural stem and progenitor cells and create a
tissue bridge after complete spinal cord transection.
Tissue Eng. Part A. 14:649-65.
Nomura H, Baladie B, Katayama Y, Morshead CM, Shoichet MS, Tator CH.
(2008) Delayed implantation of intramedullary chitosan channels containing
nerve grafts promotes extensive axonal regeneration after spinal cord injury.
Neurosurgery. 2008 Jul;63(1):127-41.
Coles-Takabe BL, Brain I, Purpura KA, Karpowicz P, Zandstra PW,
Morshead CM, van der Kooy D (2008) Don't Look: Growing clonal versus
non-clonal neural stem cell colonies. Stem Cells, 26(11):2938-44.
Tropepe V, Cheng V, Alton K, Morshead CM (2008). Embryonic mesoderm
derived stem cells with neurogenic potential can be isolated from somites
and heart, Stem Cells, 18:1533-42.
Tropepe V, Alton K, Sachewsky N, Cheng V, Kuo C, Morshead CM (2009).
Neurogenic potential of isolated precursor cells from early post-gastrula
somitic tissue. Stem Cells Dev, 18:1533-42.
Hunt J, Cheng A, Hoyles A, Jervis E, Morshead CM (2010) Cyclosporin A
has direct effects on adult neural precursor cells.
J. Neurosci, 30:2888-2896.
(with commentary in SciBX The Science Business exchange).
Scanga V, Goraltchuk A, Nussbai N, Shoichet MS, Morshead CM (2010)
Biomaterials for Neural Tissue Engineering: Chitosan supports the survival,
migration and differentiation of adult-derived neural stem and progenitor cells.
Can J Chem, 88:277-287.
Piccin D, Morshead CM (2010) Potential and pitfalls of stem cell therapy
in old age, Dis Model Mech, 3:421-425.
Erlandsson A, Lin A, Fenggang Y, Morshead CM (2010) Immunosuppression
promotes endogenous neural stem and progenitor cell migration and tissue
regeneration after ischemic injury, Exp Neurol, May 31 [Epub ahead of print]
doi:10.1016/j.expneurol.2010.05.018
Hunt J, Morshead CM (2010) Cyclosporin A enhances cell survival in neural
precursor populations in the adult central nervous system.
Mol Cell Pharmacol, 2(3):80-88.
Nomura H, Kim H, Mothe A, Zahir T, Kulbatski I, Morshead CM, Shoichet MS,
Tator CH (2010) Endogenous radial glial cells support regenerating axons after
spinal cord transection. Neuroreport, 21:871-6.
Erlandsson A, Lin A, Fenggang Y, Morshead CM (2011) Immunosuppression
promotes endogenous neural stem and progenitor cell migration and tissue
regeneration after ischemic injury, Exp Neurol, Jul;230(1):48-57
Yu F, Morshead CM (2011) Adult stem cells and bioengineering strategies
for the treatment of cerebral ischemic stroke. Curr Stem Cell Res Ther,
Apr 11 [Epub ahead of print].
Wang Y, Cooke MJ, Lapitsky Y, Wylie RG, Sachewsky N, Corbett DC,
Morshead CM, Shoichet MS (2011) Transport of epidermal growth factor in
the stroke-injured brain. J Contr Release, 149(3):225-235.
Piccin D, Morshead CM (2011) Wnt signaling regulates symmetry of
division in adult neural stem cells. Stem Cells, Dec 29
[Epub ahead of print] 29:528-38.
Cooke MJ, Wang Y, Morshead CM, Shoichet MS (2011) Controlled cortical
delivery of epidermal growth factor stimulates endogenous neural stem cell
proliferation in the stroke-injured brain. Biomaterials, 32(24):5688-97.
Guo N, Zahir T, Mothe A, Morshead CM, Shoichet MS, Katayama Y, Tator CH (2012)
The effect of growth factors and soluble Nogo66 receptor protein on transplanted
neural stem/progenitor survival and axonal regeneration after complete transection
of rat spinal cord. Cell Transplantation, 2012; 21(6):1177-97 .
Wylie R, Ahsan S, Maxwell K, Morshead CM, Shoichet MS (2011)
Three-dimensional, spatially controlled simultaneous patterning of multiple
growth factors in hydrogels. Nat Materials, 10:799-806.
Babona-Pilipos R, Droujiine I, Popovic MR, Morshead CM (2011) Neural
precursor cells undergo rapid and directed migration in response to
physiologically relevant direct current electric fields.
PLoS One, Aug 2011, 6(8) e23808.
Wang Y, Cooke MJ, Morshead CM, Shoichet MS (2012) Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury. Biomaterials 33(9)2681-2692.
Babona-Pilipos R, Popovic MR, Morshead CM. (2012) A galvanotaxis assay for analysis of neural precursor migration kinetics in an externally applied direct current electric field. JoVE, J Vis Exp. 2012 Oct 13;(68). doi:pii: 4193. 10.3791/4193.
Dibajnia P, Morshead CM. (2012) Role of neural precursor cells in promoting repair following stroke. I Acta Pharmacol Sin. 2012 Oct 15. doi: 10.1038/aps.2012.107.
Piccin D, Yu F, Morshead CM (2012) Notch signaling imparts and preserves adult neural stem cell characteristics in vitro and in vivo. Stem Cells Dev. 2013 May 15;22(10):1541-50.
Caicco MJ, Cooke MJ, Wang Y, Tuladhar A, Morshead CM, Shoichet MS (2013) A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke. J Contr Release, 166(3):197-202
Chaudhuri J, Tarulli E, Gretka V, Hoyles A, Morshead CM, Stanisz GJ.(2013) Effectiveness of MPIOs as markers for detection of migration of Bone Marrow Derived Mesenchymal Stromal Cells in a Stroke Model. J Magn Reson Imaging. 2013 Jun;37(6):1409-18.
Yu F, Li Y, Morshead CM (2013) Induced pluripotent stem cells for the treatment of stroke: Potential promise and pitfalls. Curr Stem Cell Res Ther, 8(5):407-14.
Wang Y, Cooke MJ, Sachewsky N, Morshead CM, Shoichet MS (2013) Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke. J Control Rel, 172(1):1-11
Gallagher D, Norman AA, Gauthier-Fisher A, Fujitani M, Cancino GI, Sachewsky N, Vessey JP Woltjen L, Morshead CM, Kaplan DR, Miller FD. (2013) Acutely increased maternal IL-6 mediates long-lasting changes in neural stem cell pools and adult neurogenesis. Cell Stem Cell,13(5):564-76.
Piccin D, Tufford A, Morshead CM. (2014) Senescent neural stem cells in the aged brain respond to signals from the young adult brain. Neurobiology of Aging, 35(7):1669-79.
Jeffers M, Hoyles A, Morshead CM, Corbett D (2014) Epidermal growth factor and erythropoietin infusion accelerates functional recovery in combination with rehabilitation. Stroke, 45(6): 1856-8.
Sachewsky N, Xu W, Leeder R, Rose KL, Yu F, van der Kooy D, Morshead CM. (2014) Primitive neural stem cells in the adult brain give rise to GFAP-expressing neural stem cells. Stem Cell Reports, 2(6): 810-824.
Sachewsky N, Azimi A, Morshead CM. (2014) Pro-survival factors derived from the embryonic brain promote adult neural stem cell survival. Stem Cells Dev. 23(20): 2469-2481.
Sachewsky N, Hunt J, Cooke MJ, Azimi A, Zaraneh T, Mui C, Shoichet MS, Morshead CM. Cyclosporin A enhances neural precursor cell survival through a calcineurin-independent pathway. Disease Model Mech, 7(8),953-961. *Commentary in Journal Highlights.
Book chapters
Sachewsky N, Morshead CM (2008) Adult stem cells and their role in
endogenous tissue repair in Emerging Technology Platforms for Stem Cells,
Lakshmipathy U, Chesnut J, Thyagarajan B (co-Eds).
Hoboken, New Jersey: John Wiley & Sons. 89-110.
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