UTCSP News

Feb 28, 2019

Large-scale data analysis of pain volatility from users of the “Manage My Pain” app

The advent of technology and mobile health apps has transformed the way people monitor, manage, and communicate health-related information. For pain, “Manage My Pain” is a mobile health app used by thousands of individuals to measure and manage their pain. It also has the capacity for large-scale, real-world data collection to advance pain research, treatment, and policy. In particular, data mining and machine learning methods can be used to analyze multimodal and dynamic features as well as build models for prediction. This may ultimately help us understand how pain changes across time within users and to allow for the development of effective coping strategies. 
Feb 28, 2019

Conditioned pain modulation is not unidirectional: both hyper- and hypoalgesia can arise depending on the stimulus

The advent of technology and mobile health apps has transformed the way people monitor, manage, and communicate health-related information. For pain, “Manage My Pain” is a mobile health app used by thousands of individuals to measure and manage their pain. It also has the capacity for large-scale, real-world data collection to advance pain research, treatment, and policy. In particular, data mining and machine learning methods can be used to analyze multimodal and dynamic features as well as build models for prediction. This may ultimately help us understand how pain changes across time within users and to allow for the development of effective coping strategies. 
Dec 19, 2018

Diffusion tensor imaging as a clinically translatable prognostication tool for neurosurgery

Outcomes of neurosurgical treatments for chronic pain are typically evaluated using clinical diagnostic measures. These measures, while important, are limited because they do not provide objective information about treatment effects nor offer any prognostic value. Advanced modalities of imaging may be used as a tool to monitor the effects of treatment and predict whether patients will achieve long-term pain relief.
Dec 19, 2018

Sexual dimorphism in pain hypersensitivity mechanisms is conserved across rodent species

Sex differences in the role of spinal microglia, immune cells of the central nervous system, in pain signalling have only recently been discovered using mouse models. Now, in this study conducted by UTCSP scientists in Dr. Michael Salter’s group and collaborators, they showed that this sex difference is conserved across species by examining rats. Rats are an excellent species to test if sex differences in microglia involvement of chronic pain are conserved because certain immune responses and immune-related genes differ between mice and rats.
Oct 25, 2018

Microglial pannexin-1 as a target for joint pain

Arthritis is a debilitating condition that causes chronic joint pain. While the pathology of arthritis is characterized by peripheral joint inflammation, the associated pain arises from activation of nociceptive circuits from the periphery that converge in the spinal cord. Since such activity can lead to central sensitization through activation of microglia, a central nervous system-resident immune cell, it is possible that microglia drive joint pain.
Oct 25, 2018

Prediction of response to ketamine treatment using quantitative sensory testing and brain imaging in patients with neuropathic pain

Neuropathic pain is often difficult to treat, significantly affecting quality of life. Intravenous infusion of ketamine is a growing treatment option for patients with neuropathic pain and has been shown to provide effective and long-term pain relief. However, almost half of patients that receive this therapy do not achieve analgesic effectiveness and the factors that predict response to ketamine treatment remain unknown.
Sep 27, 2018

Congratulations!

2018/19 UTCSP Pain Scientist Scholarship Recipients:
Lizbeth Ayoub (Moayedi lab)
Mariana Bueno (Stevens lab)
Katherine Halievski (Salter lab)
Alborz Noorani (Hodaie lab)

Events

CONNAUGHT SUMMER INSTITUTE IN PAIN

University of Toronto Centre for the Study of Pain
July 15-19, 2019

Massey College
University of Toronto
Application Deadline:  April 12, 2019
Click HERE for application and program details


"Dysregulation of descending pain modulatory circuits in stress-related functional pain disorders"

Presented by Dr. Frank Porreca,
Associate Department Head, Pharmacology,
College of Medicine, Tucson
Hosted by Dr. Rob Bonin
Friday, April 5, 2019
11:00 am
Room 850, 144 College Street

Leslie Dan Faculty of Pharmacy

UTCSP Translational Seminar Series presents:

"Artificial Intelligence in Pain Medicine – Current Insights and Challenges Ahead"

Wednesday, May 01, 2019
4:00pm-5:30pm
Krembil Discovery Tower
4th Floor Research Seminar Room (4KD503)
60 Leonard Ave


Click HERE for more information

Spring 2019 Systematic Review Workshop

May 15-17, 2019
This three-day workshop is intended for clinical trainees, clinicians, academics and researchers (epidemiologists, statisticians) with a general interest in the methodology of systematic reviews and for those planning to conduct a systematic review in the future. It is designed to teach participants how to plan, conduct and communicate the results of a systematic review. 
For more information and to register, visit our website at:
https://www.iwh.on.ca/events/spring-2019-systematic-review-workshop
Registration deadline is April 24, 2019

Myofacial Pain Syndrome Course

Toronto Rehabilitation Institute
Friday, May 24, 2019
Click HERE for further information and to register

UTCSP Pain Scientist Scholarship

Applications are now being accepted
Application deadline:  Friday, July 5, 2019
For complete Award details and application forms, please click on the LINK

CANANDIAN PAIN SOCIETY 40TH ANNUAL SCIENTIFIC MEETING

Toronto - April 2-5, 2019
Click HERE for complete details

IASP's Global Year For Excellence In Pain Education

January marks the launch of IASP's 2018 Global Year For Excellence In Pain Education.  IASP sponsors and promotes the Global Year For Pain, which is a year-long initiative designed to raise awareness of various aspects of pain. 

For further information, please visit the IASP website

Pain in the News

Apr 10, 2019

Peripheral and central oxidative stress in chemotherapy-induced neuropathic pain

Molecular Pain, Volume 15, Issue , January-December 2019.
Apr 10, 2019

Nerve injury elevates functional Cav3.2 channels in superficial spinal dorsal horn

Molecular Pain, Volume 15, Issue , January-December 2019.
Mar 28, 2019

Characterization of neuromas in peripheral nerves and their effects on heterotopic bone formation

Molecular Pain, Volume 15, Issue , January-December 2019.
Mar 28, 2019

Role of intraganglionic transmission in the trigeminovascular pathway

Molecular Pain, Volume 15, Issue , January-December 2019.