Sep 10, 2014

Canadian Pain Coalition News Update

Lynn  Cooper, President of the Canadian Pain Coalition was interviewed by 680 News Talk Radio yesterday - September 8, 2014.  These news clips are now posted on the Canadian Pain Coalition Website, and can be accessed by clicking on the following LINK
Jul 24, 2014

A Tipping Point for Neuropathic Pain Research

Finding new treatments for neuropathic pain has thus far proved to be incredibly difficult. Many newly developed treatments in animal models have proved ineffective when translated to humans, or failed due to undesirable side effects. Dr. Stephanie Ratte from Steven Prescott’s Lab at the Hospital for Sick Children proposes in novel research why this may be the case.
Jul 29, 2014

Mark Your Calendars!

UTCSP Trainee Meet & Greet Event
Tuesday, September 23, 2014
4:30 p.m . to 6:30 p.m.
Room 208, 155 College Street
Health Sciencies Building, U of T

Graduate students interested in and/or conducting research in the area of pain are invited to learn about the UTCSP and meet some of its members at this informal event.  Further details will be announced shortly.
Jul 29, 2014


Congratulations to Dr. Jennifer Stinson, nurse clinician scientist in the Child Health Evaluative Sciences program in the SickKids Research Institute and Nurse Practitioner with the Chronic Pain Service in the Department of Anaesthesia and Pain Medicine, as inaugural holder of the
Mary Jo Haddad Chair in Child Health on July 1, 2014.   In partnership with the Lawrence S. Bloomberg Faculty of Nursing, this Chair will create opportunities to advance pediatric nursing and generate knowledge through research that will ultimately improve current day practices and outcomes for children and adolescents
Jul 17, 2014

TEDTalk: How does your brain respond to pain?

Everyone experiences pain -- but why do some people react to the same painful stimulus in different ways? And what exactly is pain, anyway? Karen D. Davis walks you through your brain on pain, illuminating why the “pain experience” differs from person to person.
May 1, 2014

UTCSP Members Make Toronto Life's Top 30 List of Best Doctors in Toronto!

Congratulations to Allan Gordon (Pain Medicine) and John Flannery (Physiatry) for being recognized by Toronto Life Magazine as being the best in your field.


UTCSP Strategic Planning Session

Monday, November 3, 2014
12:00 noon to 5:00 p.m.
89 Chestnut Street Conference Centre

*Lunch will be served from 12:00 - 1:00

The University of Toronto Centre for the Study of Pain Translational Seminar Series presents:

Personality and Sex Differences in Chronic Pain 
Wednesday November 5, 2014
Room 270, 155 College Street

Join us for a discussion on the latest advances in research working towards personalized pain treatment
Featuring talks by:
David Lam, MD, DDS, PhD, FRCD(C), DABOMS
Josiane Mapplebeck, BSc (Hon), Master’s Student
Marie-Andrée Coulombe, PhD, Post-Doctoral Fellow
Ruma Goswami, PhD, Post-Doctoral Fellow
Remote participation will be available—Stay tuned for details
Pain Interprofessional Curriculum Design


Pain Interprofessional Curriculum Design (PICD) Workshop
hosted by the University of Toronto Centre for the Study of Pain
in association with the University of Toronto Centre for Interprofessional Education
November 12-14, 2014

National Jeans Day for Pain

Thursday, November 6, 2014
Sponsored by the Canadian Pain Coalition

For further details please click on the LINK

15th World Congress on Pain

Presented by the International Association for the Study of Pain (IASP)
October 6 - 11, 2014
Buenos Aires

For further details, please visit the IASP website by clicking on the following LINK

Global Year Against Orofacial Pain - October 2013 - October 2014

For More Information

UTCSP Annual Scientific Meeting 2015

co-sponsored with the Hospital for Sick Children's Pain Centre
Tuesday, February 10, 2015
8:00 a.m. to 1:30 p.m.
Peter Gilgan Centre for Research & Learning
Classroom 2a,b and Gallery, 686 Bay Street
The Hospital for Sick Children

Pain in the News

Sep 24, 2014

Gabapentin reverses central hypersensitivity and suppresses medial prefrontal cortical glucose metabolism in rats with neuropathic pain

Gabapentin (GBP) is known to suppress neuropathic hypersensitivity of primary afferents and the spinal cord dorsal horn. However, its supra-spinal action sites are unclear.
Sep 22, 2014

Sustained pain-related depression of behavior: effects of intraplantar formalin and complete freund┬┐s adjuvant on intracranial self-stimulation (ICSS) and endogenous kappa opioid biomarkers in rats

Intraplantar administration of complete Freund's adjuvant (CFA) and formalin are two noxious stimuli commonly used to produce sustained pain-related behaviors in rodents for research on neurobiology and treatment of pain. One clinically relevant manifestation of pain is depression of behavior and mood.
Sep 20, 2014

The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action

This study aimed to evaluate the prophylactic effect of goshajinkigan (GJG) on paclitaxel (PTX)-induced neuropathy and to elucidate the mechanism of action. There was a time-dependent irreversible decrease in pain threshold in PTX group.
Sep 12, 2014

Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse

Genetic polymorphisms, gender and age all influence the risk of developing chronic neuropathic pain following peripheral nerve injury (PNI). It is known that there are significant inter-strain differences in pain hypersensitivity in strains of mice after PNI.
Sep 11, 2014

Epigenetic regulation of spinal cord gene expression controls Opioid-Induced Hyperalgesia

The long term use of opioids for the treatment of pain leads to a group of maladaptations which includes opioid-induced hyperalgesia (OIH). OIH typically resolves within few days after cessation of morphine treatment in mice but is prolonged for weeks if histone deacetylase (HDAC) activity is inhibited during opioid treatment.
Sep 5, 2014

Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction rats

Lumbar radicular pain is categorized as a type of neuropathic pain, but its pathophysiological mechanisms are not fully understood. The substantia gelatinosa (SG) in the spinal cord dorsal horn receives primary afferent inputs and is considered to be a therapeutic target for treating neuropathic pain.