Harvey Moldofsky
MD, Dip. Psych, FRCPC
Dr. Harvey Moldofsky was formerly Professor of Psychiatry and Medicine and the founding Director of the University of Toronto Center for Sleep and Chronobiology. Currently, he is Professor Emeritus of the Faculty of Medicine and Member Emeritus, Institute of Medical Science at the University of Toronto, President and Medical Director of the Sleep Disorders Clinics of the Center for Sleep and Chronobiology, and President of the Toronto Psychiatric Research Foundation. Harvey Moldofsky earned his M.D. from the University of Toronto and pursued postgraduate training in Vancouver, Toronto, London and San Francisco. He is a Distinguished Life Fellow of the American Psychiatric Association, member emeritus of the American College of Rheumatology, the Canadian and Ontario Psychiatric Assns., and is a member of various medical and scientific societies. For more than 40 years he and his colleagues have studied the causes and treatments of illnesses characterized by chronic fatigue, musculoskeletal pain, and nonrestorative sleep, which are now known as fibromyalgia and chronic fatigue syndrome. In addition to his research on these topics, his previous publications include early studies on occupational cramp (focal dystonia), anorexia and bulimia nervosa, Gilles de la Tourette syndrome, various primary sleep-wake disorders, sleep - related medical and psychiatric disorders, their treatments, and the long term effects of chronic viral illnesses. His basic and clinical work that involve neurophysiological, neuroimmune and neuroendocrine research include those with cosmonauts and astronauts in Phase One of the International Space Station. These various fundamental and clinical studies are documented in 222 scientific publications, book chapters and monographs, and in 198 published abstracts of presentations at international scientific meetings.
University:University of Toronto
Principal Faculty:Faculty of Medicine
Principal Department/Program:Psychiatry
Fax Number:416-603-2388
Key Publications: (1) Moldofsky, H. (2009). The Significance of dysfunctions of the sleeping/waking brain to the pathogenesis and treatment of fibromyalgia syndrome. Rheumatic Disease Clinics of North America, 35, 275–283. http://www.ncbi.nlm.nih.gov/pubmed/19647142 (2) Moldofsky, H. (2010). Rheumatic Manifestations of Sleep Disorders. Current Opinion in Rheumatology. 22(1), 59-63. http://www.ncbi.nlm.nih.gov/pubmed/19935069 (3) Moldofsky, H., Inhaber, N. H., Guinta, D. R., et al. (2010). The Effects of Sodium Oxybate on Sleep Physiology and Sleep/Wake-Related Symptoms in Patients with Fibromyalgia Syndrome: A double-blind, randomized, placebo-controlled study. J Rheumatol., 37(10), 2156-66. http://www.ncbi.nlm.nih.gov/pubmed/20682669 (4) Moldofsky, H., & Patcai, J., (2011). Chronic Widespread Musculoskeletal Pain, Fatigue, Depression and Disordered Sleep in Chronic Post-SARS Syndrome: a case-controlled study. BMC Neurology, 11, 37. http://www.ncbi.nlm.nih.gov/pubmed/21435231 (5) Moldofsky, H., Harris, H. W., Archambault, T., et al. (2011). Effects of Bedtime Very Low Dose (VLD) Cyclobenzaprine (CBP) on Symptoms and Sleep Physiology in Patients with Fibromyalgia Syndrome (FM): A Double-blind, Randomized, Placebo-controlled Study. J. Rheumatol, 38(12), 2653-63. http://www.ncbi.nlm.nih.gov/pubmed/21885490