Post-transcriptional Regulation of Gene Expression

We study the post-transcriptional regulation of gene expression by RNA-binding proteins and small non-coding RNAs in the fruit fly, Drosophila melanogaster, using diverse techniques including genetics, genomics, transcriptomics, proteomics and computational biology. We also use Drosophila to understand the mechanisms underlying rare human diseases caused by mutations in RNA-binding proteins. Our research is funded by the Canadian Institutes of Health Research, Solve-RD Rare Diseases Models & Mechanisms Europe, and Rare Diseases Models & Mechanisms Canada.

’Aztec Fly' by Sergio Castrezana (courtesy of 

           “The genes are the atoms of heredity”  - Seymour Benzer