CHIPS will be an open, multicentre, international, randomised controlled trial with an intention-to-treat analysis. The study is pragmatic: that is, it will be undertaken to reflect real clinical practice rather than the very tightly controlled circumstances of explanatory trials. The pragmatic approach is important in this trial, where the interventions are policies of ‘less tight’ and ‘tight’ control, and it is not possible to blind clinicians or patients to the dBP goals of each treatment group.

Eligible women will be randomised centrally to either ‘less tight’ control (aiming for dBP of 100 mmHg) or ‘tight’ control (aiming for dBP of 85mmHg) of their hypertension.

The primary outcome is outcome for the infants, irrespective of the way the policies are administered.  The secondary outcome is outcome for the mother.

Please choose one of the following to find out more about CHIPS:

• Research Summary
• CHIPS Newsletters

 

Upcoming CHIPS Meetings

To our North American CHIPS Collaborators:

CHIPS is having a one day Collaborators’ Meeting in Toronto on Thursday February 26th, 2009 at the Delta Chelsea Hotel. A reception will be held the evening prior to the meeting on Wednesday February 25th, 2009.

Invitations have been sent to the North American Collaborators. If you did not receive one, you can download it here.

If you have any questions about this meeting, please contact Tara Morris, CHIPS Clinical Co-ordinator at chips@cw.bc.ca.


CHIPS UK Collaborators Meeting Anouncement:

CHIPS is having a one day Collaborators’ Meeting on Friday March 13th, 2009 in London at the Royal College of Physicians (RCP).

Invitations have been sent to the collaborators. If you did not receive one, you can download it here.

If you have any questions about this meeting, please contact Tara Morris, CHIPS Clinical Co-ordinator at chips@cw.bc.ca.

We would also like to tell everyone about another meeting that will be taking place the day prior to the CHIPS Meeting: OPPTIMUM is a UK based randomized trial to determine if progesterone prophylaxis to prevent preterm labour improves outcomes, and will start recruiting in early 2009. An Investigators' Meeting is planned for Thursday, 12th March 2009 at the Nevin Lecture Theatre, St Thomas' Hospital in London. All are welcome. Further information is available on the OPPTIMUM website here.

Click here to send your comments or questions about CHIPS.