Decision-makers in a variety of settings are confronted by diverse sometimes conflicting sources of evidence.  This evidence is often of unclear quality, may be affected by conflict of interest, or may not be relevant to a particular situation because of the assumptions or data sources underlying the evidence.  This course reviews five common sets of methods that decision makers may encounter; it explores common problems in the interpretation of evidence generated by these methods; and considers case(s) studies to support this exploration and to demonstrate the relevance of these methods to policy development.